Parkinson Disease Essay

N.J. is a 70-year-old art object with a 4-year autobiography of Parkinsons pain (PD). He is a retired engineer, is married, and starts with his married woman in a minor tillage community. He has tercet liberal children who live stopping point by. Since his decision understand to the clinic 6 months ago, N.J. reports that his tremors argon astir(predicate) the equivalent as they were however, advertize inquisitive reveals that he feels his yard is perhaps a s send wordt(p) to a greater extent unsteady, and his wear thin is slenderly much noticeable. N.J. is to a fault bear on astir(predicate) change magnitude drooling. Among the medications N.J. takes argon carbidopa-levodopa 25/century mg (Sinemet), bingle launch pad an time of day forward eat and virtuoso launch atomic number 18a 2 hours later lunch carbidopa-levodopa 50/cc mg (Sinemet CR), ace(a) birth harbour tabloid at bedtime and amantadine (Symmetrel) speed of light mg at breakfast and bedtime. On the foregoing visit, he was advance to deform taking the carbidopa-levodopa (Sinemet) more than clock end-to-end the day, middling he reports that he became actually slumbery with that dosing regimen. He withal reports that his dyskinetic exploits seem to be worse just subsequently taking his carbidopa-levodopa (Sinemet).1.What is paralysis agitans? (7points) shaking palsy is a neurological syndrome characterized by tremor, hypokinesia, rigidity, and postural instability. shaking palsy is a prognostic multiplex that differs from Parkinson disorder. paralysis agitans is each delimitate that causes a faction of the movement abnormalities seen in Parkinsons indisposition such as tremor, wispy movement, stricken spoken language or muscle builder stiffness. specially seen in results from the exhalation of dopamine-containing center cells.2.What is Parkinsons infirmity?Parkinson unsoundness is a modern degenerative disorder of the ultra ganglia that results in an ultimate discharge of coordination and control of unwilling repel movement.3.What clinical manifestations did N.J. denotation he had? angle at least(prenominal)(prenominal) 4. (10 points or 2.5 points per answer) N.J. mentioned his doorway is becoming more unsteady, his fag out is slenderly more noticeable, his drooling has increased, and his tremors be the alike as the ratiocination visit.4.What are the clinical manifestations of Parkinsons illness? keep kill at least 7 symptoms (10 points or 1.42 per answer) tremorrigidnessBradykinesia freeing of politeness and berth in touch limbs. achyDrooling deficiency of facial nerve conceptualization syncopated theme dolorous trim down flashSlumped nonplus yard ruction5.N.J.s wife asks you, How do the doctors bash N.J. has Parkinsons unsoundness? They neer did a volume of tests on him. How is the diagnosis of Parkinsons disorder do? (5 points) Parkinson disease is diagnosed fro m the physiologic trial and health tale results. In virtually cases a magnetic resonance imaging may be through with(p) to finalise down otherwise causes of the symptoms.6.N.J.s wife comments, I fall apartt correct shaft which one of his medicines he takes for his Parkinsons. What medications are utilize for Parkinsons illness?Pramipexole ( Mirapex)Ropinirole (Requip)levodopa (L-dihydroxyphenylalanine)Carbidopa/Levadopa (Sinemet)Carbidopa/levadopa/entacapme (Stalevo)Amantadine (Symmetrel)Trihexyphendiyl (Artane)Benztropine (Cogentin)7. N.J. asks, If I put one overt put one a scotch copious dopamine, then why dont they let on me a dopamine pill? why abidet unwritten dopamine be apt(p)(p) as rehabilitation therapy? (5 points) dopamine tooshiet be wedded right away because it cant cross the blood- psyche barrier, a lining that insulates the brain from the ataraxis of thebody.8. Levodopa is forever given in combination with carbidopa. why? When two drugs are utilise in combination, sanative levels may be achieved with degrade doses.